Aimed at the requirement of 1553B board in the aviation field, put forward a new design method of 1553B BM board design based on HI6110. First, the 1553B bus and the HI6110 chip was introduced, and then the some design aspects ware given, such as the processor designed, HI6110 designed, FPGA designed and FLASH designed. At last, the software functions model and the software flow was expounded. The results showed this new method has advantages in reliability, cost, etc.