In order to accurately obtain the pulsating pressure distribution on the surface of the model in the wind tunnel experiment, the multi-channel data acquisition system needs to be integrated with the microphone array, and it is of great significance to develop a multi-channel and miniaturized data acquisition system due to the limitation of the model volume. In this paper, a 128-channel integrated data acquisition (DAQ) system is developed, which adopts PCB stack design and high-performance small-volume data processing unit, optimizes the multi-channel structure, avoids the problem of excessive volume caused by parallel connection of multiple core boards in the past, and realizes the integration and miniaturization of DAQ system, and the results show that the size of the designed DAQ system is 18 cm×12 cm; The FPGA chip is used to control the serial communication of 16 AD7606 chips to realize the synchronous acquisition of 128 channels, and the acquisition signal is uploaded to the Gigabit Ethernet analysis program and multi-channel synchronous acquisition program designed by LabVIEW, which realizes the real-time display and data storage of the waveform, and the experimental results show that the DAQ system can achieve a sampling rate of 110 KSPS per channel, and the sampling relative error of each channel is less than 0.18%.