In order to improve the operational effectiveness evaluation of far-fire strike system, simulation analysis is carried out based on far-fire strike system. Based on the multi-scheme simulation data, the combined evaluation model of far-fire strike system combat effectiveness based on analytic network process-grey relational analysis (ANP-GRA) is proposed to evaluate the combat effectiveness. The evaluation results show that the method can select a reasonable evaluation scheme based on the simulation data, which has a good reference significance.