The optical load of the laser system is susceptible to the vibration of the platform, which causes serious technical difficulties in beam control and high-precision acquisition and tracking. In this paper, aiming at the problems of " invisible ", " unstable " and " inaccurate " of laser system in complex dynamic environment, a high vibration reduction and stabilization platform suitable for large optical load was designed. Based on the superior variable damping performance of magnetorheological elastomer, a three-degree-of-freedom magnetorheological vibration isolation device was designed, and the structural design of magnetorheological damper was carried out. Based on the theoretical analysis and finite element calculation method, the vibration system dynamics simulation program was developed by using Matlab software, and the vibration isolation and buffering performance of the vibration isolation device was studied and verified. The simulation results show that the high vibration reduction and stabilization platform designed in this paper meets the requirements of vibration reduction and buffering of optical platform and upper equipment, and has good vibration isolation and buffering performance. It can solve the key problem of maneuvering tracking and aiming of large optical load, and improve the dynamic beam control and high-precision acquisition and tracking ability of laser system.