According to the rescue command requirements of nuclear and radiation accidents, chemical accidents, biological safety incidents, a nuclear, biological and chemical (NBC) rescue command box is designed. This paper analyzes the meaning and capability requirements of the use of the box group by the armed police anti-chemical warfare unit, expounds the hardware composition and main functions of the box group, and studies and designs the system software system and information flow. This study can provide a reference for the rescue of the armed police chemical defense unit.