In order to improve the management ability of hospital financial information, an integrated platform of hospital financial information is established by using information technology, and a unified database is used to store and process the financial information data. This paper designs the architecture of hospital financial information integration platform based on information integration, establishes a financial online reimbursement system based on structured query language (SQL) technology, analyzes the business process of hospital financial reimbursement, and takes SQL Server 2005 as the background database. Hospital financial reimbursement process based on browser/server (B/S) mode. The experimental results show that the response time of the system is less than 4.96 s for single service and less than 65 s for mixed service; The data throughput of the system is 8 Mbps, and the data processing efficiency is 87%, which is better than the data processing results of similar systems and the operation response performance of general systems, and can meet the needs of hospital financial management, and provide a reference for the establishment of an information-based hospital financial management information platform.