Aiming at the problem that the result of operational effectiveness evaluation of weapon equipment can guide its operational application, a grey target theory comprehensive model for operational effectiveness evaluation of weapon equipment is proposed. Deng’s grey target theory is given and its application defects in equipment operational effectiveness evaluation are analyzed. Comprehensive target degree model of equipment operational effectiveness evaluation based on TOPSIS method concept is introduced, including the construction of virtual grey target, comprehensive target degree model based on grey correlation degree, etc. Operational effectiveness evaluation examples of 4 ultra-short wave ground communication countermeasure systems are given. The analysis results show that the comprehensive evaluation method is reasonable and effective.