Aiming at the urgent demand of anti-UAV swarm, the idea of building an air-ground cooperative intelligent countermeasure system is proposed. The function, composition and working principle of the system are described, and the research direction of key technologies such as intelligent perception and decision-making is clarified. Based on the air-ground collaborative intelligent command and control system, a variety of unmanned reconnaissance and weapon systems in the air and on the ground are comprehensively used to achieve rapid discovery, accurate tracking, intelligent identification and damage interception of UAV swarm, which effectively improves the effectiveness of systematic confrontation. The results show that the system can provide ideas for our army to develop intelligent anti-UAV swarm combat force system.