In view of the problems of long service life and high failure rate of imported equipment in the production of initiating explosive devices, an automatic production line of initiating explosive devices with independent intellectual property rights was designed. Control technologies such as “full configuration” technology of man-machine interface programming, redundancy technology of double touch screens, interlocking technology of communication between 2 screens and intrinsic safety field bus are adopted to realize the flexibility of production varieties in the production line and unmanned operation in the production site, so as to ensure the safe production of the production line. The results show that the production line can improve the intrinsic safety of equipment production, improve labor productivity, reduce production and management costs, and enhance the manufacturing capacity of enterprises.