Aiming to the urgent needs of the military storage construction, a cargo location optimization scheme of military stereoscopic warehouse based on lookout algorithm is proposed. Considering the differences between military materials and civilian products in variety, efficiency, compatibility, quality and safety performance, and other aspects, the paper chooses the efficiency of delivery and shelf stability as the objective function through the analysis of the management of multiple kinds of cargo location, establishes the optimization model by using the lookout algorithm, designs the corresponding algorithm flow and obtains the cargo location optimization scheme. The effectiveness of the model is verified by the example, and the application prospect of the modeling method in the military storage management is demonstrated.