Aiming at the problem of batch technology preparation scheduling optimization of multi-types surface-to-air missiles, a genetic algorithm model optimization is proposed. The optimization model of missile batch technical preparation scheduling is constructed, and the genetic algorithm is used to solve the model. Through the scheduling optimization of 2 types of missiles prepared against the ground, the shortest completion time of technical preparation of 5 missiles and the arrangement sequence of each work are obtained. The results of case analysis show that the model can calculate the shortest completion time of missile preparation according to the change of personnel and equipment quantity, which provides the basis for decision-makers in wartime to judge when the batch of missiles can complete technical preparation and launch distribution and transportation.