In order to deal with the problem of lack of quantitative data, a quantitative analysis method was proposed to specify the command span of mixed terminal aerial defense group based on information command means. Firstly, affecting factors of mixed integration command span was qualitatively analyzed, which mainly refereed to the command subject, object and means. Secondly, based on the Graicunas formula in management, the information efficiency factor, the command difficulty index and the collaboration difficulty index were introduced to calculate the amount of command and control relationships. It is used to measure the complexity of the work of command and control, by comparing with the empirical value of traditional command span. Finally, an example of capital terminal aerial defense group was used to illuminate the proposed method, which deduced a value of 6 in mixed integration command span. It shows that the proposed quantitative analysis method can provide foundation for determining the mixed integration command span.