Aiming at the problems about rough information exchanging, opaque process, low operating efficiency in the production and management in CNC machine tools, and in order to adapt to the development tide of flexible manufacturing technology, designed the DNC system based on FANUC CNC machine tools. The system utilizes the ORACEL database to manage the data of machine tools, and the C/S structure is used as an application mode to ensure the security and efficiency of communication. Use industrial Ethernet for communication, the system is based on the .NET platform, utilize the C# programming language, and the task processing adopts the multi-threaded concurrent mode. The results show that the system can improve efficiency of the machine tool program and data management and realize refinement, digitization and information management of the factory manufacturing process.