Aiming at many factors affecting the effectiveness of missile weapon equipment maintenance support, the effectiveness of equipment maintenance support based on AHP and fuzzy comprehensive evaluation method is evaluated. According to the method of fuzzy comprehensive evaluation, the evaluation model of missile weapon equipment maintenance support effectiveness is constructed. The weight of evaluation index is determined by analytic hierarchy process. The support effectiveness of accomplishing maintenance support task is analyzed comprehensively. The capability level of each element in the maintenance support system of missile weapon equipment is evaluated, and the model is solved and validated. The calculation results show that this method can effectively evaluate the maintenance effectiveness of missile weapon equipment maintenance system quantitatively.