In order to effectively guide the structure design of aircraft, obtain the intermediate parameters which can not be obtained in wind tunnel test, and reduce the number of wind tunnel tests, based on the advantages of existing simulation literature. The geometry shape of the aircraft, non-structured meshing, fluid dynamic parameters and non-powered flight trajectory data were processed and calculated with Pro/Engineer, ANSA, Fluent and Matlab. Hydrodynamic parameters of high-precision calculations were completed in 96 cases by MPI parallel computing and JOU batch programming compiled personally with 10 millions of mesh in support of high-powered workstation hardware. The longitudinal motion equations were solved and the flight trajectory simulation was completed with Matlab programming compiled personally combined with typical The Fourth-Order Range-Kutta Method and Lagrange interpolation algorithm, the flight trajectory simulation was completed, which can efficiently guide the design of mine structural, the number of wind-tunnel testing was reduced, and the intermediate parameters were got access which can’t get by wind-tunnel testing. The development cycle was effectively shortened, the development funding were saved.