In order to solve the low precision of conventional method to calculate the missile pitch angle and drift angle, the high precision method of using 2 photo-electric theodolites direct intersection calculation is presented. Firstly the calculation equation is obtained based on relationship between the ground coordinate system and the image coordinate system. Then computational model and precision estimation of pitch angle and drift angle is achieved by putting 2 photo-electric theodolites measuring elements into calculation equation. According to the model, the missile head and tail coordinate error is not used in calculating error in this paper. Apply the method to the ×× task, the results show that the results tendency of the two methods are consistent, but the precision of this paper is obviously higher than that of the conventional method, and this method can be applied in engineering practice.