According to operating personnel adopt manual master-slave robot to take cover bottled radioactive liquid for sub-dividing deficiency, based on robot automatic operation technology, pipette, electronic balance, a set of lid bottled radioactive liquid automatic loading system is developed. Main automatic operation process include: send bottle, open, cover, remove liquid and put back and sampling mouth replacement such action. Pipette is used to absorb and drainage. Electronic weighing scales used for liquid. Its institutions is mainly Legalized by 3 three freedom robots, 3 turntables and 2 holding blocks etc. The result shows that it increased the precision-loading, efficiency and level of automation of lid bottled radioactive liquid, which significantly reduce the radiation damage.