A design scheme of 1553B bus remote terminal board based on HI-6130 is presented in this paper, it has solved the urgent needs of miniaturization, low power consumption of 1553B bus airborne equipment, which is necessary for the air force. A feasible design method of 1553B terminal mode data bus interface board is developed through the design of hardware circuit, analysis and simulation of software drivers. The test results show that data transmission is reliable and stable, the design has been successfully applied in the certain airborne equipment, which well meets the requirements for airborne equipment miniaturization and low power consumption.