Aiming at the low manufacturing efficiency and low acceptability of traditional joint chamber die, adopt application process and method of CAD/CAM/DNC integrated technology based on MasterCAM, put forward the requirement configuration and working process of this technology. Taking joint chamber die as example, use MasterCAM software to carry out the model 3D entity modeling, technical parameter setting, simulation processing and automatic generating NC program. Then, use the DNC communication technology to input the procedure on line into NC tool for process.