Aiming at the vibration problem caused by unreasonable design of double-column lifter, the causes of vibration are analyzed and the design optimization is carried out. The causes of vibration were analyzed through the basic force, bending vibration and torsional vibration, and the structure of double-column lifter was optimized from the 2 aspects of column layout and guide wheel layout. The verification results show that the design can control the vibration within the allowable range, even eliminate the vibration, and then eliminate the economic losses and safety problems caused by vibration.