In order to adapt to the impact of the development of high and new technology on military operations, strengthening on research of our army unmanned battlefield, improve the professional construction capacity of UAV, and put forward the development direction of UAV professional construction of combat in the future. By analyzing the application and problems of UAV in the conflict between Nagorno-Karabakh and combining with the operational characteristics of UAV, this paper is analyzed from 5 aspects: the operational advantages of UAV, cluster construction, core technology autonomy and control, function integration and establishment system construction. The results show that it is of great significance to strengthen the professional construction of UAV and the autonomous control of UAV technology.