In order to enhance the ability to destroy ships, the effect of aluminum-oxygen ratio (Al/O) of CL-20-based aluminum-containing explosives on the underwater energy output structure was investigated. Design different Al/O CL-20 based aluminum explosive formulations, use underwater explosion power test, analyze the underwater energy output structure of several mixed explosive formulations and influence principle of the Al/O to CL-20 based aluminized explosives on underwater shock wave energy, underwater bubble energy and underwater energy output structure. The experimental results show that the underwater shock wave energy, bubble energy and total energy of CL-20-based aluminized explosives increase first and then decrease with the increase of Al/O, and the total energy of underwater explosion has an Al/O of about 0.75. The maximum value is approximately 6.43 MJ/kg.