According to the CL-20 high explosive energy feature, through the selection of raw materials and processes, the CL-20 was coated and granulated by kneading-granulation method to prepare CL-20 based press-fit type anti-overload temperature and pressure explosive. The test results show that the prepared CL-20 base press-type anti-overload temperature and pressure explosive has good coating quality, high bulk density, and smooth particles. The test shows that the composite insensitive system can significantly reduce the CL-20 elemental explosive mechanical sensitivity.